منابع مشابه
Defining Mixed Phenotypic Leukemias
The majority of acute leukemias can be classified by the lineage of origin of blast cells as either myeloid, B Lymphoblastic (B-ALL) or T lymphoblastic. Acute leukemias are categorized by flow cytometry and now, increasingly, molecular results which help to determine whether the leukemia arises from the myeloid or lymphoid series. There does exist, however, an undefined or ambiguous group of le...
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متن کاملPhenotypic Cutoffs: Defining Resistance and Virologic Outcomes
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OBJECTIVES To describe the spectrum of toxicity of baclofen in overdose, and investigate dose-related clinical effects. METHODS Consecutive baclofen overdoses were identified from a prospective database of all poisoning admissions presenting to a regional toxicology service. Ingestion was corroborated on more than one occasion and from multiple sources. Demographic, clinical and outcome varia...
متن کاملThe phenotypic spectrum of SCN8A encephalopathy.
OBJECTIVE SCN8A encodes the sodium channel voltage-gated α8-subunit (Nav1.6). SCN8A mutations have recently been associated with epilepsy and neurodevelopmental disorders. We aimed to delineate the phenotype associated with SCN8A mutations. METHODS We used high-throughput sequence analysis of the SCN8A gene in 683 patients with a range of epileptic encephalopathies. In addition, we ascertaine...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2018
ISSN: 0013-9580
DOI: 10.1111/epi.13986