Defining the Newborn Blood Spot Screening Reference Interval for TSH: Impact of Ethnicity
نویسندگان
چکیده
منابع مشابه
Screening for disease in the newborn: the evidence base for blood-spot screening.
This paper reviews the evidence of benefit resulting from newborn screening in Australia as well as for some of those disorders not yet included in the Australian panels, and discusses briefly disorders under active consideration for inclusion in the screening panels.There is solid evidence of benefit from newborn screening for phenylketonuria, congenital hypothyroidism, cystic fibrosis, and ov...
متن کاملScreening of newborn babies: from blood spot to bedside.
In The Lancet, Shakila Thangaratinam and colleagues report fi ndings from a systematic review and metaanalysis of pulse oximetry screening for critical congenital heart defects in asymptomatic newborn babies. The investigators note that the overall sensitivity of pulse oximetry (76·5%, 95% CI 67·7–83·5) compared with other methods of detection (eg, prenatal ultrasound and routine physical exam)...
متن کاملNewborn blood spot screening in four countries: stakeholder involvement.
While newborn blood spot screening has historically been viewed as a public health success, the potential harms and benefits are more finely balanced for new conditions being considered for program expansion. We highlight complex issues that must be addressed in policy decisions, which in turn requires a consideration of many stakeholder perspectives. Using national policy documents from the Un...
متن کاملNewborn dried blood spot screening: residual specimen storage issues.
Traditional newborn dried blood spot screening (NDBS) has expanded in recent years to include upwards of 50 different conditions in many states. Once the screening tests are complete, the residual blood specimens (RBSs) that remain are most often available for quality assurance and public health research. The articles by Botkin et al1 and Bombard et al2 contained in this issue of Pediatrics inv...
متن کاملSchool based screening for hypothyroidism in Down's syndrome by dried blood spot TSH measurement.
OBJECTIVE To determine the feasibility of annual hypothyroid screening of children with Down's syndrome by measuring thyroid stimulating hormone (TSH) on dried blood spots at school, and to describe the outcome in positive children. DESIGN Establishment of a register of school children with Down's syndrome, and procedures for obtaining permission from parents, annual capillary blood samples, ...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2016
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2016-1822