Defining synonymous codon compression schemes by genome recoding
نویسندگان
چکیده
منابع مشابه
Synonymous codon usage in chloroplast genome of Coffea arabica
Synonymous codon usage of 53 protein coding genes in chloroplast genome of Coffea arabica was analyzed for the first time to find out the possible factors contributing codon bias. All preferred synonymous codons were found to use A/T ending codons as chloroplast genomes are rich in AT. No difference in preference for preferred codons was observed in any of the two strands, viz., leading and lag...
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Observing differences between DNA or protein sequences and estimating the true amount of substitutions from them is a prominent problem in molecular evolution as many analyses are based on distance measures between biological sequences. Since the relationship between the observed and the actual amount of mutations is very complex, more than four decades of research have been spent to improve mo...
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In most bacteria, synonymous codons are not used with equal frequencies. Different factors have been proposed to contribute to codon usage preference, including translational selection, GC composition, strand-specific mutational bias, amino acid conservation, protein hydropathy, transcriptional selection and even RNA stability. The review discusses these factors and their contribution to bias i...
متن کاملThe distinction between recoding and codon reassignment.
IN several recent reports, the term ‘‘recoding’’ is used to describe the phenomenon of codon reassignment (e.g., Charriere et al. 2006; McCutcheon et al. 2009). McCutcheon et al. (2009) misuse the term in numerous locations, suggesting that confusion is systemic and not inadvertent. This provokes us to clarify the distinction between these two natural phenomena. Reassignment and recoding are di...
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ژورنال
عنوان ژورنال: Nature
سال: 2016
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature20124