Deferiprone (Ferriprox)
نویسندگان
چکیده

 CADTH recommends that Ferriprox should be reimbursed by public drug plans for the treatment of patients with transfusional iron overload due to sickle cell disease (SCD) or other anemias if certain conditions are met.
 covered based on criteria used each programs deferasirox (DFX), orally administered SCD and anemias.
 only prescribed clinicians who have expertise managing cost is not more than lowest chelation therapy treat
منابع مشابه
Efficacy and safety of deferiprone (Ferriprox), an oral iron-chelating agent, in pediatric patients
BACKGROUND Iron overload is a predictable and life-threatening complication in patients dependent on the regular transfusion of RBCs. The aims of this study were to investigate the efficacy and safety of deferiprone in a variety of pediatric hematologic and/or oncologic patients with a high iron overload. METHODS SEVENTEEN PATIENTS (AGE: 1.1-20.4 years; median: 10.6 years) from 7 hospitals wh...
متن کاملNEW DRUGS NEW DRUGS Ferriprox Reduces Excess Iron
NEW DRUGS Ferriprox Reduces Excess Iron Deferiprone (Ferriprox, Apo-Pharma, Inc.) has been approved to treat iron overload resulting from blood transfusions in patients with thalassemia who have responded inadequately to previous chelation therapy. Thalassemia is a genetic blood disorder that causes anemia. Patients with thalassemia have excess iron levels from frequent blood transfusions, a se...
متن کاملUpdate on a patient with superficial siderosis on deferiprone.
Deferiprone Superficial siderosis (SS) is a neurodegenerative condition caused by hemosiderin deposition on the surface of the brain, cranial nerves, and spinal cord. SS is an exceptionally rare condition characterized by a triad of hearing loss, ataxia, and myelopathy. The most common etiologies that lead to SS are trauma, previous surgical procedures, dural tears, and tumors of the central ne...
متن کاملAntioxidant targeting by deferiprone in diseases related to oxidative damage.
The design of antioxidant pharmaceuticals is a major challenge for the treatment of many clinical conditions and in aging. Free radical damage (FRD) is primarily catalysed by iron catalytic centers. Most of the natural and synthetic antioxidants are ineffective in inhibiting FRD because of the achievement of low concentrations at the affected tissues. Despite that many chelators inhibit FRD in ...
متن کاملDeferiprone targets aconitase: Implication for Friedreich's ataxia treatment
BACKGROUND Friedreich ataxia is a neurological disease originating from an iron-sulfur cluster enzyme deficiency due to impaired iron handling in the mitochondrion, aconitase being particularly affected. As a mean to counteract disease progression, it has been suggested to chelate free mitochondrial iron. Recent years have witnessed a renewed interest in this strategy because of availability of...
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ژورنال
عنوان ژورنال: Canadian journal of health technologies
سال: 2023
ISSN: ['2563-6596']
DOI: https://doi.org/10.51731/cjht.2023.563