Defective mismatch repair in the pathogenesis of low-grade appendiceal mucinous neoplasms and adenocarcinomas
نویسندگان
چکیده
منابع مشابه
Low-grade appendiceal mucinous neoplasm and endometriosis of the appendix
BACKGROUND A distended, mucous-filled appendix is known as an appendiceal mucocele. They are a rare form of an appendiceal mass and develop from both benign and malignant processes. Mucoceles can develop secondarily to an obstruction, such as from a fecalith, scarring or, rarely, endometriosis. Only 12 cases of non-neoplastic appendiceal mucoceles caused by endometriosis have been previously de...
متن کاملAppendiceal mucinous neoplasms: controversial issues.
Low grade appendiceal mucinous neoplasms can spread to the peritoneum as pseudomyxoma peritonei even though they are not obviously invasive in the appendix. During the past several decades, several problematic issues surrounding this enigmatic tumor have been debated in the literature, including appropriate nomenclature for the appendiceal tumors and their peritoneal metastases. In this article...
متن کاملAn incidental discovery of low-grade appendiceal mucinous neoplasm.
A 65-year-old man with a history of hyperplastic polyps underwent a surveillance colonoscopy, which revealed a large, smooth cystic bulge at the appendicular orifice (Figure 1). Subsequently, a computed tomography (CT) of the abdomen with contrast revealed an appendiceal mucocele measuring 13.3 x 4.5 cm (Figures 2a and 2b). Because of the abnormal imaging findings, an elective laparoscopic appe...
متن کاملLow-Grade Appendiceal Mucinous Neoplasm Presenting as an Adnexal Mass
Appendiceal tumors are rare, late diagnosed neoplasms that may not be differentiated from adnexal masses even by advanced imaging methods and other diagnostic procedures. They may be asymptomatic and remain undiagnosed until surgery. We report a case of an 80-year-old postmenopausal woman presenting with a pelvic mass and a history of weight loss. The patient underwent laparotomy which revealed...
متن کاملLow-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge
Primary appendiceal mucinous lesions are uncommon and represent a spectrum from nonneoplastic mucous retention cysts to invasive adenocarcinoma. Low-grade appendiceal mucinous neoplasms (LAMNs) represent an intermediate category on this spectrum and can be classified according to whether or not they are confined to the appendix. Although LAMNs are frequently confined to the appendix, they can a...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2004
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.3800212