Deep hypothermic arrest: Observations on later development in children
نویسندگان
چکیده
منابع مشابه
Deep hypothermic circulatory arrest.
Effective cerebral protection remains the principle concern during aortic arch surgery. Hypothermic circulatory arrest (HCA) is entrenched as the primary neuroprotection mechanism since the 70s, as it slows injury-inducing pathways by limiting cerebral metabolism. However, increases in HCA duration has been associated with poorer neurological outcomes, necessitating the adjunctive use of antegr...
متن کاملPerioperative management of deep hypothermic circulatory arrest.
m d t r e t n a a h c n i l r t 1 t d u t 2 g g l t HE GOAL OF this article is to provide a review of deep hypothermic circulatory arrest (DHCA), covering major isues including pathophysiology of ischemic injury, organ protecion (both pharmacologic and nonpharmacologic), temperature ontrol, and perfusion methods. The purpose of this review is to erve as a resource for board review or as introdu...
متن کاملDeep hypothermic circulatory arrest and the effects on the brain
The effect of deep hypothermic circulatory arrest (DHCA) in children with congenital heart disease on subsequent cognitive and motor performance is of great importance, and a number of case reports and patient series document neurological impairment associated with DHCA(1,2). However, only one large, controlled investigation of this issue has been conducted. Between 1988 and 1992, 171 infants w...
متن کاملApoptotic neuronal death following deep hypothermic circulatory arrest in piglets.
BACKGROUND Deep hypothermic circulatory arrest (DHCA), as used in infant heart surgery, carries a risk of brain injury. In a piglet DHCA model, neocortical neurons appear to undergo apoptotic death. Caspases, cytochrome c, tumor necrosis factor (TNF), and Fas play a role in apoptosis in many ischemic models. This study examined the expression of these factors in a DHCA piglet model. METHODS T...
متن کاملAccuracy of core temperature measurement in deep hypothermic circulatory arrest.
Deep hypothermia is an effective technique for neuroprotection in cardiac surgery. However, standard body temperature measurement may deviate from actual brain temperature. Therefore, we simultaneously measured brain and core temperatures during neurosurgical interventions in hypothermic circulatory arrest to determine its accuracy. Between 1994 and May 2007, 26 patients (12 female, mean age 46...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1979
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)40918-5