Decoding insulin resistance and metabolic syndrome for promising therapeutic intervention
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چکیده
منابع مشابه
Decoding insulin resistance and metabolic syndrome for promising therapeutic intervention.
Metabolic syndrome, also known as insulin resistance syndrome, has become a major public health problem worldwide. It consists of obesity, hyperglycemia, hyperinsulinemia, dyslipidemia, and hypertension. Metabolic syndrome is a major risk factor for the development of type 2 diabetes mellitus, which currently afflicts 22 million Americans and over 100 million Chinese (Alberti et al. 2005, Corni...
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Combination of metabolic abnormalities in patients with high vascular risk is well known since long time. In his Banting lecture Reaven used the term Syndrome X for the description of the coexistence of these metabolic diseases. Other names as e.g. Deadly Quartet and insulin resistance syndrome emphasised the consequences and the possible cause of this syndrome. Most of the authors accept that ...
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Combination of metabolic abnormalities in patients with high vascular risk is well known since long time. In his Banting lecture Reaven used the term “Syndrome X” for the description of the coexistence of these metabolic diseases. Other names as e.g. “Deadly Quartet” and insulin resistance syndrome emphasised the consequences and the possible cause of this syndrome. Most of the authors accept t...
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Insulin resistance (IR) and hyperinsulinemia are hallmarks of the metabolic syndrome, as are central adiposity, dyslipidemia, and a predisposition to type 2 diabetes, atherosclerotic cardiovascular disease, hypertension, and certain cancers. Regular exercise and calorie restriction have long been known to increase insulin sensitivity and decrease the prevalence of these disorders. The subsequen...
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The metabolic syndrome consists of a cluster of metabolic disorders, many of which promote the development of atherosclerosis and increase the risk of cardiovascular disease events. Insulin resistance may lie at the heart of the metabolic syndrome. Elevated serum triglycerides commonly associate with insulin resistance and represent a valuable clinical marker of the metabolic syndrome. Abdomina...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2014
ISSN: 0022-0795,1479-6805
DOI: 10.1530/joe-13-0584