منابع مشابه
Decoding Cilia Function Defining Specialized Genes Required for Compartmentalized Cilia Biogenesis
The evolution of the ancestral eukaryotic flagellum is an example of a cellular organelle that became dispensable in some modern eukaryotes while remaining an essential motile and sensory apparatus in others. To help define the repertoire of specialized proteins needed for the formation and function of cilia, we used comparative genomics to analyze the genomes of organisms with prototypical cil...
متن کاملN-acetylcysteine effects on sinonasal cilia function
The mucociliary transport system plays an important role in the clearance of excessive mucus and inhaled foreign materials from the respiratory tract. Airway epithelium’s ciliary structure is a part of the natural defense system that protects the respiratory system by propelling debris laden mucus. The mucus flow is generated by the vigorous asymmetric beating of the cilia, which can be named a...
متن کاملConserved function for embryonic nodal cilia.
How left right handedness originates in the body plan of the developing vertebrate embryo is a subject of considerable debate. In mice, a left right bias is thought to arise from a directional extracellular flow (nodal flow) that is generated by dynein-dependent rotation of monocilia on the ventral surface of the embryonic node. Here we show that the existence of node monocilia and the expressi...
متن کاملSensory roles of neuronal cilia: cilia development, morphogenesis, and function in C. elegans.
In the free-living nematode Caenorhabditis elegans, cilia are found on the dendritic endings of sensory neurons. C. elegans cilia are classified as 'primary' or 'sensory' according to the '9+0' axonemal ultrastructure (nine doublet outer microtubules with no central microtubule pair) and lack of motility, characteristics of '9+2' cilia. The C. elegans ciliated nervous system allows the animal t...
متن کاملStructural maintenance and chemosensory function of human airway motile cilia
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ژورنال
عنوان ژورنال: Cell
سال: 2004
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(04)00412-x