منابع مشابه
Adipose tissue: cell heterogeneity and functional diversity.
There are two types of adipose tissue in the body whose function appears to be clearly differentiated. White adipose tissue stores energy reserves as fat, whereas the metabolic function of brown adipose tissue is lipid oxidation to produce heat. A good balance between them is important to maintain energy homeostasis. The concept of white adipose tissue has radically changed in the past decades,...
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Obesity is not synonymous with insulin resistance. Why some but not all individuals develop insulin resistance with weight excess is not clear, but a number of plausible hypotheses with ample support now exist. This article reviews regional fat distribution, inflammation, lipotoxicity/ectopic fat and impaired adipogenesis as leading theories as to why excess body weight has the potential to pro...
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Most lethal solid tumors including hepatocellular carcinoma (HCC) are considered incurable due to extensive heterogeneity in clinical presentation and tumor biology. Tumor heterogeneity may result from different cells of origin, patient ethnicity, etiology, underlying disease, and diversity of genomic and epigenomic changes which drive tumor development. Cancer genomic heterogeneity thereby imp...
متن کاملKatja Röper: Deciphering tissue origami
JCB • VOLUME 215 • NUMBER 2 • 2016 140 As a teenager growing up in West Berlin, Katja Röper witnessed the fall of the Berlin Wall from Checkpoint Charlie, and the opening of the Brandenburg Gate, amazing moments in history that reshaped her home country. During these years, her parents— a mineralogist and a nurse—were also shaping her future career as a scientist by encouraging her fascination ...
متن کاملAdipose Tissue
Morphological changes associated with mobilization of lipid were studied in epididymal adipose tissue from fasted and from alloxan diabetic rats. In both groups of animals a decrease in lipid content was accompanied by the formation of complex frond-like cytoplasmic processes and of loops and folds of basement membrane which extended from cell surfaces. These changes, evident after 1 day of fas...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 2017
ISSN: 0077-8923
DOI: 10.1111/nyas.13398