DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1
نویسندگان
چکیده
منابع مشابه
DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1
BACKGROUND Several studies have found that DDR2 is up-regulated in many tumor types and facilitates tumor progression. However, the role of DDR2 in hepatocellular carcinoma (HCC) progression and its downstream signaling pathways remain unclear. METHODS DDR2 expression was assessed in several cell lines and 112 pairs of HCC and matched adjacent noncancerous liver tissues. Clinical significance...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2015
ISSN: 1756-9966
DOI: 10.1186/s13046-015-0218-6