Dataset on interactions of membrane active agents with lipid bilayers
نویسندگان
چکیده
منابع مشابه
Alcohol Interactions with Lipid Bilayers.
We investigate the structural changes to lipid membrane that ensue from the addition of aliphatic alcohols with various alkyl tail lengths. Small angle neutron diffraction from flat lipid bilayers that are hydrated through water vapor has been employed to eliminate possible artefacts of the membrane curvature and the alcohol's membrane-water partitioning. We have observed clear changes to membr...
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Appearing as a computational microscope, MD simulation can ‘zoom in’ to atomic resolution to assess detailed interactions of a membrane protein with its surrounding lipids, which play important roles in the stability and function of such proteins. This study has employed the molecular dynamics (MD) simulations, to determine the effect of added DMPC or DMTAP molecules on the structure of D...
متن کاملLattice simulations of phase morphology on lipid bilayers: renormalization, membrane shape, and electrostatic dipole interactions.
When liquid phases coexist at equilibrium but are not driven to minimize domain interfacial contact energy, the resulting patterns of phase domains can have important implications for living cells. In this study we explore some of the interactions and conditions that produce the stable patterned phases that are observed in model lipid mixtures. By use of Monte Carlo simulations we find that bac...
متن کاملLipid domains control myelin basic protein adsorption and membrane interactions between model myelin lipid bilayers.
The surface forces apparatus and atomic force microscope were used to study the effects of lipid composition and concentrations of myelin basic protein (MBP) on the structure of model lipid bilayers, as well as the interaction forces and adhesion between them. The lipid bilayers had a lipid composition characteristic of the cytoplasmic leaflets of myelin from "normal" (healthy) and "disease-lik...
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We characterize the differences between supported and unsupported lipid bilayer membranes using a mesoscopic simulation model and a simple particle-based realization for a flat support on to which the lipids are adsorbed. We show that the nanometer roughness of the support affects membrane binding strength very little. We then compare the lipid distributions and pressure profiles of free and su...
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ژورنال
عنوان ژورنال: Data in Brief
سال: 2020
ISSN: 2352-3409
DOI: 10.1016/j.dib.2020.105138