منابع مشابه
Aspirin for cancer chemoprevention: still a headache?
Almost 7 million Americans, with the full blessing of their cardiologists, now take daily aspirin to prevent heart attacks, according to the Aspirin Foundation of America. But should we take aspirin to prevent cancer? Answers remain elusive, but the current consensus is: not yet, not even for colorectal cancer, where the strongest evidence exists. " We still have a long way to go to be certain ...
متن کاملAn aspirin a day: the allure (and distraction) of chemoprevention.
1782 Editorials | JNCI DOI:10.1093/jnci/djs462 © The Author 2012. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: [email protected]. 2. El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 2007;132(7):2557–2576. 3. Gale M Jr, Foy EM. Evasion of intracellular host defence by hepatitis...
متن کاملAspirin and other NSAIDs as chemoprevention agents in melanoma.
Melanoma incidence is increasing and, despite recent therapeutic advances, the prognosis for patients with metastatic disease remains poor. Thus, early detection and chemoprevention are promising strategies for improving patient outcomes. Aspirin (acetylsalicylic acid) and other nonsteroidal anti-inflammatory drugs (NSAID) have demonstrated chemoprotective activity in several other cancers, and...
متن کاملAspirin in the chemoprevention of colorectal neoplasia: an overview.
Considerable evidence supports the effectiveness of aspirin for chemoprevention of colorectal cancer (CRC) in addition to its well-established benefits in the prevention of vascular disease. Epidemiologic studies have consistently observed an inverse association between aspirin use and risk of CRC. A recent pooled analysis of a long-term posttrial follow-up of nearly 14,000 patients from four r...
متن کاملChemoprevention of colorectal cancer by aspirin: a cost-effectiveness analysis.
BACKGROUND & AIMS The aim of the study is to compare the cost-effectiveness of aspirin and colonoscopy in the prevention of colorectal cancer. METHODS A Markov process is used to follow a hypothetical cohort of 100,000 subjects aged 50 years until death. Four strategies are compared: (1) no intervention, (2) colonoscopy once per 10 years and every 3 years in subjects with polyps, (3) chemopre...
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ژورنال
عنوان ژورنال: Nature Reviews Clinical Oncology
سال: 2014
ISSN: 1759-4774,1759-4782
DOI: 10.1038/nrclinonc.2014.35