DAFS: simultaneous aligning and folding of RNA sequences via dual decomposition

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DAFS: simultaneous aligning and folding of RNA sequences via dual decomposition

MOTIVATION It is well known that the accuracy of RNA secondary structure prediction from a single sequence is limited, and thus a comparative approach that predicts a common secondary structure from aligned sequences is a better choice if homologous sequences with reliable alignments are available. However, correct secondary structure information is needed to produce reliable alignments of RNA ...

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relation between rna sequences, structures, and shapes via variation networks

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2012

ISSN: 1460-2059,1367-4803

DOI: 10.1093/bioinformatics/bts612