D2 or non D2-lymphadenectomy in gastric cancer

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Learning Curve for D2 Lymphadenectomy in Gastric Cancer

Background. D2 lymphadenectomy is a demanding technique which is associated with high morbidity in the West. We report our experience with D2 lymphadenectomy after a training period in Japan. Methods. Prospective, descriptive study in 133 consecutive patients undergoing radical gastrectomy for gastric adenocarcinoma from 2005 to 2011. We analysed the number of lymph nodes removed, observed morb...

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Prognostic significance of distal subtotal gastrectomy with standard D2 and extended D2 lymphadenectomy for locally advanced gastric cancer.

This study was conducted to investigate prognosis and survival of patients undergoing distal subtotal gastrectomy with D2 and D2+ lymphadenectomy for patients with locally advanced gastric cancer. Overall survival rates of 416 patients with locally advanced gastric cancer were compared between D2 and D2+ lymphadenectomy. Univariate analysis and multivariate analysis was used to identify signifi...

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Indirect Comparison Showed Survival Benefit from Adjuvant Chemoradiotherapy in Completely Resected Gastric Cancer with D2 Lymphadenectomy

Background. Little data on directly comparing chemoradiotherapy with observation has yet been published in the setting of adjuvant therapy for resected gastric cancer who underwent D2 lymphadenectomy. The present indirect comparison aims to provide more evidence on comparing the two approaches. Methods. We conducted a systematic review of randomized controlled trials, extracted time-to-event da...

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Satisfactory surgical outcome of T2 gastric cancer after modified D2 lymphadenectomy

OBJECTIVE Though D2 lymphadenectomy has been increasingly regarded as standard surgical procedure for advanced gastric cancer (GC), the modified D2 (D1 + 7, 8a and 9) lymphadenectomy may be more suitable than D2 dissection for T2 stage GC. The purpose of this study is to elucidate whether the surgical outcome of modified D2 lymphadenectomy was comparable to that of standard D2 dissection in T2 ...

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Meta-analysis of effectiveness and safety of D2 plus para-aortic lymphadenectomy for resectable gastric cancer.

Study selection Randomised controlled trials (RCTs) that compared D2 plus para-aortic lymphadenectomy (including dissection of middle para-aortic lymph nodes, 16a2, 16b1) with standard D2 lymphadenectomy in patients with resectable, biopsydiagnosed, gastric adenocarcinoma were eligible for inclusion in the review. Studies had to report more than one of the specified outcome measures. The primar...

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ژورنال

عنوان ژورنال: Oncología (Barcelona)

سال: 2004

ISSN: 0378-4835

DOI: 10.4321/s0378-48352004000400005