D-penicillamine therapy and interstitial lung disease in scleroderma. a long-term followup study
نویسندگان
چکیده
منابع مشابه
Interstitial lung disease in scleroderma
Pulmonary involvement is quite frequent in the development of progressive systemic sclerosis (PSS), a disease that affects the skin and internal organs and may present in various forms, especially as interstitial lung disease (ILD) or pulmonary hypertension (PH).(1) The incidence of pulmonary involvement varies depending on the population and on the methodology used for the diagnosis, reaching ...
متن کاملScleroderma-related interstitial lung disease
Scleroderma-related interstitial lung disease (SSc-ILD) is a pulmonary fibrosing disorder characterized by systemic inflammation and progressive scarring of the lungs that leads to respiratory failure. Although certain immunosuppressive therapies may slow disease progression, current treatment strategies are not curative; consequently, SSc-ILD continues to be a major cause of morbidity and mort...
متن کاملThe Assessment of Health-Related Quality of Life in Scleroderma-Interstitial Lung Disease
Introduction: Pulmonary involvement is the most common cause of mortality and disability in patients with systemic sclerosis and it significantly affects the quality of life in these patients. Therefore, early diagnosis and treatment of pulmonary involvement seems necessary in patients with SSc. In this study, we aimed to assess the health-related quality of life (HRQoL) in patients with Sclero...
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Eighty-five patients with rheumatoid disease were treated with penicillamine, and 69 completed more than one year's treatment. The main reason for discontinuing penicillamine in the 16 patients who withdrew was adverse reaction. The number of adverse reactions, however, declined when patients were given lower maintenance doses of penicillamine. In those who tolerated the drug the results of tre...
متن کاملLong Term Effects of Cyclophosphamide Treatment on Lung Function and Survival in Scleroderma Patients with Interstitial Lung Disease
BACKGROUND Scleroderma (SSc) patients with active interstitial lung disease (ILD) experience a decline in lung function and increased mortality; cyclophosphamide (CYC) therapy may stabilize lung function at one and two years follow-up. Long-term lung function and survival outcomes of SSc patients with ILD following CYC treatment remain largely unknown. METHODOLOGY We reviewed records of SSc p...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1987
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780300607