D-penicillamine-induced membranous nephropathy
نویسندگان
چکیده
منابع مشابه
D-penicillamine induced membranous glomerulonephritis in a child with Wilson's disease.
Dear Editor, Wilson’s disease (WD) is a rare autosomal recessive disorder of copper homeostasis with a prevalence of 30 affected individuals per million population. Treatment is based on oral chelating agents such as D-penicillamine. Despite its effectiveness, Dpenicillamine presents significant adverse effects. Among them is proteinuria and nephrotic syndrome. An 11 yearold boy was admitted wi...
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Rheumatoid arthritis can be a very mutilating disease and, as a result, the likelihood of patients with rheumatoid arthritis requiring surgery and anaesthesia is increased. D-penicillamine (D-Pen) has been used in the treatment of rheumatoid arthritis and Wilson's disease since the early 1960s. Its true mode of action is unknown, but it appears to modify the immune response. Treatment with D-Pe...
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A forty-three year old female applied for a $200,000 ten year decreasing term policy. She admitted a history of "kidney disorder" on the application. She was not being treated or having any symptoms but stated that she was under observation. A routine paramed exam showed height 5’4", weight 140 lbs, and blood pressure 110/70. The BCP was normal. The HOS showed 210 mg/dl proteinuria. A reflex de...
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Forty-one patients with a nephrotic syndrome and biopsy-proven membranous nephropathy were administered a 3 to 6-month course of cyclosporine (CsA; 4 to 5 mg/kg per day). Differential solute clearances were used to evaluate glomerular function before and after therapy. CsA lowered median proteinuria by 56%, from 7.3 to 3.2 g/24 h (P < 0.0001). Corresponding mean increments in serum albumin, imm...
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ژورنال
عنوان ژورنال: Indian Journal of Nephrology
سال: 2014
ISSN: 0971-4065
DOI: 10.4103/0971-4065.132024