Cytotoxic Effects of Cucurbitacin I and Ecballium elaterium on Breast Cancer Cells

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The Cultivation and Cucurbitacin Content of Ecballium elaterium (L.)

Introduction: Although Ecballium elaterium (L.) A. Rich., is considered as a minor crop in the Cucurbitaceae family. However, its medicinal virtues (3, 8) and its resistance to pests and diseases (6, 7), have made the plant a suitable candidate to improve crop quality in Cucurbitaceae species. Cultivation studies were aimed at assessing the growth of the plant and the variation of cucurbitacins...

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Purification of Cucurbitacins D, E, and I from Ecballium Elaterium (L.) A. Rich Fruits and Study of Their Cytotoxic Effects on the AGS Cell Line

Background: The plant Ecballium elaterium (L.) A. Rich, belongs to the Cucurbitaceae family which occupies an important position in traditional medicine prescriptions. It has been reported that a freeze-dried aqueous extract of E. elaterium fruits has cytotoxic effects on the AGS human stomach adenocarcinoma cell line. We here focused on anticancer effects of the main chemicals purified from E....

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Cytotoxic and anti-proliferative effects of Rosa beggeriana Schrenk extracts on human liver and breast cancer cells

Objective: Rosa beggeriana Schrenk has been consumed in Iranian traditional medicine. In contrary to its close species (e.g. R. canina), there is no data on its medicinal properties. Therefore, we explored possible cytotoxic effects of R. beggeriana against two cancer cell lines. Materials and Methods: The cytotoxic and anti-pro...

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Nanoliposomal formulation of Ecballium elaterium Extract: Cytotoxic Evaluation against Human Gastric Adenocarcinoma (AGS) Cell Line

Objective(s): The aim of this study was to determine cytotoxic effect of nanoliposomal form of lyophilized aqueous extract of Ecballium elaterium fruit on gastric cell line (AGS) using cell viability tests. Methods: An aqueous extract of the fruits of Ecballium elaterium was prepared. Nanoliposomal form was also prepared by thin-film hydration...

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Keratoconjunctivitis and Periorbital Edema due to Ecballium elaterium

PURPOSE To report on a case of keratoconjunctivitis with periorbital edema after accidental exposure to undiluted juice of Ecballium elaterium fruit during the ripening season of this plant. METHODS Case report. RESULTS Keratoconjunctivitis with Descemet's membrane folds and superficial upper corneal well-defined edematous areas were noted after an Ecballium elaterium fruit burst and its ju...

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ژورنال

عنوان ژورنال: Natural Product Communications

سال: 2018

ISSN: 1934-578X,1555-9475

DOI: 10.1177/1934578x1801301108