Cytotoxic Cardenolides from the Leaves of Calotropis gigantea
نویسندگان
چکیده
منابع مشابه
A new cytotoxic pregnanone from Calotropis gigantea.
A new pregnanone, named calotropone (1), was isolated from the EtOH extract of the roots of Calotropis gigantea L. together with a known cardiac glycoside. The structures were elucidated by a study of their physical and spectral data. Compounds 1 and 2 displayed inhibitory effects towards chronic myelogenous leukemia K562 and human gastric cancer SGC-7901 cell lines.
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From different plant parts of Calotropis species (C. gigantea and C. procera), various classes of compounds such as oxypregnanes, terpenoids, sterols, cardenolides and flavonoids have been isolated. Of these compounds, the cardenolides stand out as many of them have anticancer properties. Cardenolides are C23 steroids with a five-membered unsaturated butyrolactone ring consisting of a steroid n...
متن کاملCytotoxic Compounds from Calotropis gigantea (Linn.) and Amoora rohituka (Roxb.)
Calotropis gigantea (Linn) and Amoora rohituka (Roxb.) have long been used in folkloric medicine for the treatment of various ailments in Bangladesh. The present study was designed to investigate the cytotoxicity of isolated compounds from these two plants. Two compounds, named β-boswellic acid (compound-1) and 2-methoxy-14-calamenenone (compound-2) were isolated from the flowers of Calotropis ...
متن کاملcytotoxic compounds from calotropis gigantea (linn.) and amoora rohituka (roxb.)
calotropis gigantea (linn) and amoora rohituka (roxb.) have long been used in folkloric medicine for the treatment of various ailments in bangladesh. the present study was designed to investigate the cytotoxicity of isolated compounds from these two plants. two compounds, named β-boswellic acid (compound-1) and 2-methoxy-14-calamenenone (compound-2) were isolated from the flowers of calotropis ...
متن کاملCalotropis gigantea- botanical, pharmacological view
Calotropis gigantea is a big shrub; it’s looking like a small tree, sports clusters of waxy flowers that are either white or lavender in colour found. Each flower consists of five pointed petals and a small, elegant "crown" rising from the center, which holds the stamens. This articles is viewed the botanical survey and full details of the plant of calotropis gigantea. It has oval, light green ...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2010
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.58.725