Cytoplasmic Ribonucleoprotein Foci in Eukaryotes: Hotspots of Bio(chemical)Diversity
نویسندگان
چکیده
منابع مشابه
Cytoplasmic Ribonucleoprotein Foci in Eukaryotes: Hotspots of Bio(chemical)Diversity
The life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They ar...
متن کاملCytoplasmic Ribonucleoprotein Components of the Novikoff Hepatoma
Prominent nucleoprotein sedimentation boundaries were demonstrable in cytoplasmic extracts of Novikoff hepatoma. Fractionation of the homogenates by differential centrifugation or a density gradient method revealed that 65 to 75 per cent of the cytoplasmic ribonucleic acid was present in the form of free ribonucleoprotein particles. After purification by differential centrifugation in dilute bu...
متن کاملCytoplasmic foci are sites of mRNA decay in human cells
Understanding gene expression control requires defining the molecular and cellular basis of mRNA turnover. We have previously shown that the human decapping factors hDcp2 and hDcp1a are concentrated in specific cytoplasmic structures. Here, we show that hCcr4, hDcp1b, hLsm, and rck/p54 proteins related to 5'-3' mRNA decay also localize to these structures, whereas DcpS, which is involved in cap...
متن کاملStructure and function of nuclear and cytoplasmic ribonucleoprotein particles.
NUCLEAR R1BONUCLEOPROTEIN PA TICLES .................................................................... 461 Evidence for, and lsolation of, hnRNP Particles ....................................................... 461 General Structural Features of hnRNP articles ...................................................... 467 Proteins of hnRNP Particles ..................................................
متن کاملNuclear and cytoplasmic localization of a lectin-ribonucleoprotein complex.
31. Koquemore, E. I).. Dell, A., Morris, H. K., I’anico, M., Reason, A. J., Savoy, I,.-A,, Wistow, G. J.. Zigler, J. S., Earles, H. J. & Hart, G. W. (1 992) J. Hiol. Chem. 267, 5 5 5 5 0 3 32. Klemenz, R., Frohli, E., Steiger, K. H., Schafer, K. & Aoyama, A. (1991) I’roc. Natl. Acad. Sci. U.S.A. 88, 3 0 523 65 6 33. Henko, L). M., Haltiwanger, K. S., Hart, G. W. & Gibson, W. (1088) I’roc. Natl....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Comparative and Functional Genomics
سال: 2012
ISSN: 1531-6912,1532-6268
DOI: 10.1155/2012/504292