Cytokines in proliferative vitreoretinopathy
نویسندگان
چکیده
منابع مشابه
Proliferative vitreoretinopathy.
PURPOSE. The migration, proliferation, differentiation, and adhesion of cells and other cellular functions are influenced by the surrounding extracellular matrix, in normal and wound-healing conditions. The matrix metalloproteinases (MMPs) are a family of enzymes that degrade and remodel the extracellular matrix and, thus, play a central role in the wound-healing process. Proliferative vitreore...
متن کاملApoptosis in proliferative vitreoretinopathy.
PURPOSE To study the involvement of apoptosis using different apoptosis markers in PVR pathogenesis. METHODS The presence of mRNA coding for Fas, Fas ligand (FasL), and TNF-related apoptosis inducing ligand (TRAIL) was investigated in vitreous samples from 46 consecutive patients-25 with PVR, 11 with retinal detachment (RD) not complicated by PVR, and 10 with macular hole (MH)-using RT-PCR. F...
متن کاملKeratinocyte transglutaminase in proliferative vitreoretinopathy.
PURPOSE Proliferative vitreoretinopathy (PVR) is an excessive wound-healing process and the major complication in rhegmatogenous retinal detachment. The present study was designed to investigate the expression of keratinocyte transglutaminase (kTgase) in PVR membranes and retinal pigment epithelial (RPE) cells and to evaluate its expression in response to growth factors known to be increased in...
متن کاملCytokines in vitreous humor: interleukin-6 is elevated in proliferative vitreoretinopathy.
PURPOSE To measure the levels of interleukins (IL) 1 beta, 6, and 8, and tumor necrosis factor-alpha (TNF alpha) in the vitreous of patients with proliferative vitreoretinopathy (PVR), proliferative diabetic retinopathy (PDR), vitreous hemorrhage, and macular pucker. METHODS Vitreous samples were collected, undiluted, from patients with PVR, PDR of varying severity, and miscellaneous lesions ...
متن کاملThe Pathogeny of Proliferative Vitreoretinopathy.
Proliferative vitreoretinopathy (PVR) is the most important complication of rhegmatogenous retinal detachment (RRD) and the main cause of RRD surgery failure. This is a review of recent literature data, which concerns PVR pathogeny and risk factors. The occurrence of pre- and subretinal membranes is a consequence of retinal pigment epithelial cells activation and migration, with concomitant par...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Eye
سال: 1991
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.1991.126