Cytogenetic and molecular biomonitoring of a Portuguese population exposed to pesticides
نویسندگان
چکیده
منابع مشابه
Toxic Effects of Pesticides: a Review on Cytogenetic Biomonitoring Studies
Pesticides constitute a heterogeneous category of chemicals specifically designed for the control of pests, weeds or plant diseases. Biological monitoring provides a useful tool to estimate the genetic risk deriving from an integrated exposure to a complex mixture of chemicals. Studies available in scientific literature have essentially focused on cytogenetic end-points to evaluate the potentia...
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The frequency of chromosomal aberrations was studied in the peripheral blood lymphocytes of 65 radiology technologists CRT) working at hospitals chronically exposed to x-rays. Although film dosimetry did not show the maximal annual permitted dose in any of the examined subjects, cytogenetic analysis detected fairly high levels of chromosomal aberrations in R T compared to unexposed controls...
متن کاملCytogenetic monitoring in a population occupationally exposed to pesticides in Ecuador.
We analyzed the incidence of structural and numerical chromosomal aberrations (CAs) in workers of a plantation of flowers located in Quito, Ecuador, in South America. This study included 41 individuals occupationally exposed to 27 pesticides, some of which are restricted in many countries and are classified as extremely toxic by the World Health Organization; among these are aldicarb and fenami...
متن کاملCytogenetic Monitoring of Farmers exposed to pesticides in Colombia.
We have monitored 30 pesticide-exposed workers and 30 matched controls for expression of chromosome aberrations (CA) and sister chromatid exchanges (SCE) in their lymphocytes. Peripheral blood cultures were set up within 3 hr after the collection of samples, and four cultures were set up from each donor. For CA analysis, 100 complete metaphase cells from each donor were evaluated. For the SCE a...
متن کاملMicronucleus analysis in a Portuguese population exposed to pesticides: preliminary survey.
The general population is exposed in their everyday life to different chemicals namely to pesticides. Many of these compounds are capable of inducing mutations in DNA and lead to several diseases including cancer. With this study we intended to evaluate DNA damage inflicted by pesticide exposure in a population occupationally exposed to those chemicals by means of the micronucleus (MN) test. Th...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2006
ISSN: 0267-8357,1464-3804
DOI: 10.1093/mutage/gel039