Cytogenetic abnormalities and azoospermia factor (AZF)microdeletions in infertile men from Kuwait
نویسندگان
چکیده
منابع مشابه
Cytogenetic abnormalities and azoospermia factor (AZF) microdeletions in infertile men from Kuwait
Approximately 15% of couples in the reproductive age group worldwide are affected by infertility, and it is estimated that about 40-50% of infertilities are of male origin. Genetic factor accounts for 10-15% of severe male infertility, including chromosomal aberrations and single gene mutations (Ferlin et al, 2006). After the Klinfelter syndrome, Y chromosomal microdeletions are the most freque...
متن کاملSomatic cytogenetic and azoospermia factor gene microdeletion studies in infertile men.
The objective of the present study was to determine the frequency of somatic chromosomal anomalies and Y chromosomal microdeletions (azoospermia factor genes, AZF) in infertile males who seek assisted reproduction. These studies are very important because the assisted reproduction techniques (mainly intracytoplasmic sperm injection) bypass the natural selection process and some classical chromo...
متن کاملCytogenetic Abnormalities in Infertile Men in the Prešov Region (Slovakia)
Chromosome anomalies belong to genetic factors, which participate on etiology of reproductive failure. The aim of the study was to investigate the frequency of chromosome abnormalities in infertile men in the Prešov region in Slovakia (1998-2014). Karyotyping using G-banding and C-banding methods was performed in 1426 subjects including 948 infertile men and 478 controls. Karyotype analyses rev...
متن کاملFrequency of Y chromosome microdeletions and chromosomal abnormalities in infertile Thai men with oligozoospermia and azoospermia.
AIM To investigate the possible causes of oligozoospermia and azoospermia in infertile Thai men, and to find the frequencies of Y chromosome microdeletions and cytogenetic abnormalities in this group. METHODS From June 2003 to November 2005, 50 azoospermic and 80 oligozoospermic men were enrolled in the study. A detailed history was taken for each man, followed by general and genital examinat...
متن کاملChromosomal studies in infertile men with oligozoospermia & non-obstructive azoospermia.
BACKGROUND & OBJECTIVE Chromosomal anomalies have been postulated to be as one of the principal genetic factors in male infertility. Cytogenetic evaluation of men with severely compromised semen parameters reveals an increased incidence of chromosomal aberrations when compared with the normal population. The objective of this study was to determine the chromosomal constitution and sperm charact...
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ژورنال
عنوان ژورنال: Journal of Molecular and Genetic Medicine
سال: 2010
ISSN: 1747-0862
DOI: 10.4172/1747-0862.1000040