Cytochrome P450 Function in Pediatric Sepsis-Induced Multiple Organ Failure.♦ 179
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چکیده
منابع مشابه
Peripheral nerve function in sepsis and multiple organ failure.
Forty-three patients who had sepsis and multiple organ failure (critical illness) were studied prospectively to determine the incidence and severity of peripheral nerve function and to correlate such function with a number of variables. Electrophysiologic studies indicated a primary axonal degeneration of motor and sensory fibers in 30 (70 percent). Fifteen (30 percent) had the clinical signs o...
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STUDY OBJECTIVES To determine the circulating anti-inflammatory cytokine interleukin 10 (IL-10) response during the development of sepsis-induced multiple organ failure in children. DESIGN Prospective study. SETTING University pediatric ICU. PATIENTS Fifty-three consecutive children with sepsis and 15 critically ill children without sepsis. INTERVENTIONS Plasma IL-10, interleukin 6 (IL-...
متن کاملMarked hypercalcaemia in sepsis-induced multiple organ failure.
HNF-1b mutations. Most importantly, patients with an HNF-1b mutation may also be at risk of developing renal cell carcinomas, since recent evidence suggests that HNF-1b is a tumour suppressor gene [5]. In conclusion, patients with unexplained nephropathy and/or renal cysts should be routinely screened for an HNF-1b mutation in order to differentiate the RCAD syndrome from diabetic nephropathy. ...
متن کاملThree Hypothetical Inflammation Pathobiology Phenotypes and Pediatric Sepsis-Induced Multiple Organ Failure Outcome.
OBJECTIVES We hypothesize that three inflammation pathobiology phenotypes are associated with increased inflammation, proclivity to develop features of macrophage activation syndrome, and multiple organ failure-related death in pediatric severe sepsis. DESIGN Prospective cohort study comparing children with severe sepsis and any of three phenotypes: 1) immunoparalysis-associated multiple orga...
متن کاملPediatric septic shock and multiple organ failure.
In the last 5 years, the understanding of the epidemiology and pathogenesis of pediatric sepsis, septic shock, and multiple organ failure has expanded greatly. There has also been a substantial increase in the number of successful randomized trials in which success has been measured as reduction in mortality in adults, children, and newborns. This article discusses these advances, updating the ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1997
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199704001-00199