CYP2C9 polymorphism in patients with epilepsy: genotypic frequency analyzes andphenytoin adverse reactions correlation
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چکیده
منابع مشابه
CYP2C9 polymorphism in patients with epilepsy: genotypic frequency analyzes and phenytoin adverse reactions correlation.
OBJECTIVE CYP2C9 is a major enzyme in human drug metabolism and the polymorphism observed in the corresponding gene may affect therapeutic outcome during treatment. The distribution of variant CYP2C9 alleles and prevalence of phenytoin adverse reactions were hereby investigated in a population of patients diagnosed with epilepsy. METHOD Allele-specific PCR analysis was carried out in order to...
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ژورنال
عنوان ژورنال: Arquivos de Neuro-Psiquiatria
سال: 2011
ISSN: 0004-282X
DOI: 10.1590/s0004-282x2011000200002