Cyclosporin therapy for severe scleritis.

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Cyclosporin therapy for severe scleritis.

To ascertain the efficacy of systemic cyclosporin therapy in the management of scleritis we performed an open, uncontrolled study of the use of this drug in severe refractory disease. Five of seven patients whose disease had previously been poorly controlled with a combination of corticosteroids and immunosuppressive drugs responded to cyclosporin therapy (10 mg/kg/day). Systemic side effects o...

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Cyclosporin for severe ulcerative colitis.

BACKGROUND About one-third of patients with severe ulcerative colitis do not respond to conventional therapy and require urgent colectomy. It was recently shown that cyclosporin is effective in some of these patients. OBJECTIVES To review the current experience of six hospitals in central Israel that used cyclosporin in patients with severe ulcerative colitis. METHODS The files of all 32 pa...

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Subpalpebral lavage antibiotic treatment for severe infectious scleritis and keratitis.

OBJECTIVE To report the subpalpebral lavage therapy for the treatment of infectious scleritis and keratitis. METHOD Six patients were admitted for treatment of severe infectious scleritis and keratitis and were initiated on the subpalpebral lavage system after showing no improvement with topical fortified antibiotics. A continuous antibiotic lavage was applied until clinical sterility was ach...

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Silymarin flavonoids and cyclosporin A: Effective co-therapy?

Milk thistle (Silybum marianum) is a native plant of Mediterranean Sea areas. Silymarin, an extract from its seeds, is used in various liver diseases for its hepatoprotective effects. It contains silymarin flavonoids (SF) such as silybin, silydianin and silychristin. Cyclosporin A (CsA) is widely used as an immunosuppressant in organ transplantations. Its other applications in many autoimmune d...

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Resolution of Anterior Scleritis after Periodontal Therapy

Scleritis is a chronic inflammation that involves the outermost coat and the skeleton of the eye. Scleritis may be associated with a systemic or immune mediated disease and it might be caused by an infection, trauma or drug reaction. This case presents a patient with generalized chronic periodontitis and anterior diffuse scleritis. A 30-year-old female complained of pain and persistent scleriti...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1989

ISSN: 0007-1161

DOI: 10.1136/bjo.73.9.743