Cyclophilin A and viral infections

Cyclophilin and Viruses: Cyclophilin as a Cofactor for Viral Infection and Possible Anti-Viral Target

Cyclophilin (CyP) is a peptidyl prolyl cis/trans isomerase, catalyzing the cis-trans isomerization of proline residues in proteins. CyP plays key roles in several different aspects of cellular physiology including the immune response, transcription, mitochondrial function, cell death, and chemotaxis. In addition to these cellular events, a number of reports demonstrated that CyP plays a critica...

HLA-KIR Interactions and Immunity to Viral Infections

Host genetic factors play a central role in determining the clinical phenotype of human diseases. Association between two polymorphic loci in human genome, human leukocyte antigen (HLA) and killer cell immunoglobulin-like receptors (KIRs), and genetically complex infectious disease, particularly those of viral etiology, have been historically elusive. Hence, defining the influence of genetic di...

P-53: Chronic Viral Infections and Infertility in Male

Background: The most common sexually transmitted diseases and the economic and social health problem throughout the world. However, vaccine coverage and antibiotic therapy and the development of programs to prevent and control major causes of acute and chronic diseases, pregnancy complications and infertility remains. Acute and chronic systemic viral infections can lead to infertility and perma...

Studies on Avian Viral Infections in Iran

Viral infections and wounds

The effects of viral infections on wounds, be they surgical or due to thermal injury, remain ill-defined. The purpose of this paper is to describe briefly the effects of surgical wounds, burn wounds and viral infections on the immune system and to review what has been reported in the literature on viral infections and wounds in the immunocompetent host to gain a greater understanding of their t...