Cyclopentane-Peptide Nucleic Acids for Qualitative, Quantitative, and Repetitive Detection of Nucleic Acids
نویسندگان
چکیده
منابع مشابه
Nucleic Acids: Qualitative Modeling
Knowledge about RNA three-dimensional structure is essential to RNA function comprehension and manipulation. Due to difficulties associated with physical RNA structure elucidation techniques, such as x-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy, it is not surprising that predictive methods are increasingly gaining popularity. Consequent to many genome sequencing proje...
متن کاملMagnetic peptide nucleic acids for DNA targeting.
A versatile synthetic platform for the efficient immobilization of PNAs on magnetic iron oxides, providing magnetic nanosensors for selective DNA recognition, is presented.
متن کاملAntisense properties of peptide nucleic acids.
PNA is a nucleic acid analog with an achiral polyamide backbone consisting of N-(2-aminoethyl)glycine units (figure 1). The purine or pyrimidine bases are linked to the each unit via a methylene carbonyl linker (1-3) to target the complementary nucleic acid (4). PNA binds to complementary RNA or DNA in a parallel or antiparallel orientation following the Watson-Crick base-pairing rules (5-7). T...
متن کاملNucleic Acids
The first isolation of what we now refer to as DNA was accomplished by Johann Friedrich Miescher circa 1870. He reported finding a weakly acidic substance of unknown function in the nuclei of human white blood cells, and named this material "nuclein". A few years later, Miescher separated nuclein into protein and nucleic acid components. In the 1920's nucleic acids were found to be major compon...
متن کاملNucleic acids.
In: Dyer A, Hudson HG and Williams PA (eds) Ion Exchange Processes: Advances and Applications, p. 39. Cambridge, UK: The Royal Society of Chemistry. Lehto J and Harjula R (1997) Selective separation of radionuclides from nuclear waste solutions with inorganic ion exchangers, React Funct Polym (in press). Navratil JD (1989) Ion exchange technology in spent fuel reprocessing. Journal of Nuclear S...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2012
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac3026459