Cyclic AMP as a negative regulator of hormonally induced lactogenesis in mouse mammary gland organ culture.
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چکیده
منابع مشابه
Cyclic AMP as a negative regulator of hormonally induced lactogenesis in mouse mammary gland organ culture.
In organ cultures of mammary glands from mice in midpregnancy, addition of both insulin and prolactin induces a marked accumulation of alpha-lactalbumin, whereas the augmentation of casein synthesis requires the presence of insulin, prolactin, and cortisol. Addition of 0.5 mM dibutyryl cyclic AMP resulted in complete inhibition of alpha-lactalbumin accumulation and partial inhibition of casein ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1980
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.77.4.2093