Customized Steady-State Constraints for Parameter Estimation in Non-Linear Ordinary Differential Equation Models
نویسندگان
چکیده
منابع مشابه
Customized Steady-State Constraints for Parameter Estimation in Non-Linear Ordinary Differential Equation Models
Ordinary differential equation models have become a wide-spread approach to analyze dynamical systems and understand underlying mechanisms. Model parameters are often unknown and have to be estimated from experimental data, e.g., by maximum-likelihood estimation. In particular, models of biological systems contain a large number of parameters. To reduce the dimensionality of the parameter space...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2016
ISSN: 2296-634X
DOI: 10.3389/fcell.2016.00041