Current methodologies utilized in the conduct of randomized clinical trials
نویسندگان
چکیده
منابع مشابه
Clinical trials registries are under-utilized in the conduct of systematic reviews: a cross-sectional analysis
BACKGROUND Publication bias is a major threat to the validity of systematic reviews. Searches of clinical trials registries can help to identify unpublished trials, though little is known about how often these resources are utilized. We assessed the usage and results of registry searches reported in systematic reviews published in major general medical journals. METHODS This cross-sectional a...
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“A properly planned and executed clinical trial is a powerful experimental technique for assessing the effectiveness of an intervention” (1, p. 2). This paper will discuss the issues related to the proper planning and execution of a multicenter clinical trial. The importance of a detailed protocol and manual of operations should not be underestimated. The fundamental principles are relatively s...
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I read with interest the article on the effect of antiseptics on the colonization rate of central venous catheters, published in the recent issue of your Journal.1 Although the topic is very important, the study suffers from many shortcomings, the most important of which is low study power. Assuming expected prevalence rates of 22% and 17% in the control and treatment groups (an effect size of ...
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ژورنال
عنوان ژورنال: Future Science OA
سال: 2018
ISSN: 2056-5623
DOI: 10.4155/fsoa-2018-0043