Current and Potential Therapies for Ocular Neovascular Diseases
نویسندگان
چکیده
منابع مشابه
Prion diseases - current theories and potential therapies: a brief review.
Prion diseases are a group of infectious diseases that cause lethal neurodegenerative disorders in both humans and animals. Affected patients usually die within one year from the appearance of the first clinical abnormalities. Unfortunately, no viable treatment options are available for prion diseases. The aim of this review is to describe the underlying prion disease pathology and discuss the ...
متن کاملBroad Spectrum Antiangiogenic Treatment for Ocular Neovascular Diseases
UNLABELLED Pathological neovascularization is a hallmark of late stage neovascular (wet) age-related macular degeneration (AMD) and the leading cause of blindness in people over the age of 50 in the western world. The treatments focus on suppression of choroidal neovascularization (CNV), while current approved therapies are limited to inhibiting vascular endothelial growth factor (VEGF) exclusi...
متن کاملBevacizumab for ocular neovascular diseases: a systematic review.
CONTEXT AND OBJECTIVE Many eye diseases involve increased local levels of vascular endothelial growth factor (VEGF), and there are several therapeutic strategies for them. Thus, the aim of this study was to evaluate the effectiveness and safety of bevacizumab for treating eye diseases involving increased local levels of VEGF, as the assumed pathophysiological mechanism. DATA SOURCES The follo...
متن کاملPlacental growth factor and its potential role in diabetic retinopathy and other ocular neovascular diseases
The role of vascular endothelial growth factor (VEGF), including in retinal vascular diseases, has been well studied, and pharmacological blockade of VEGF is the gold standard of treatment for neovascular age-related macular degeneration, retinal vein occlusion and diabetic macular oedema. Placental growth factor (PGF, previously known as PlGF), a homologue of VEGF, is a multifunctional peptide...
متن کاملrole of vascular endothelial growth factors in ocular neovascular diseases
the most important progress in the field of retinal diseases during recent years might be the introduction of pharmacotherapy. age-related macular degeneration for instance was an irreversible disease leading to permanent anatomical and functional changes in the macula up to the previous decade; however, the use of anti-vascular endothelial growth factor agents (anti-vegfs) not only stops the p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical & Experimental Pharmacology
سال: 2013
ISSN: 2161-1459
DOI: 10.4172/2161-1459.1000e122