Cure is not enough: One slogan, two paradigms for pediatric oncology

One is not enough.

In both prokaryotic and eukaryotic organisms, repressors and activators are responsible for regulating gene expression. The lac operon is a paradigm for understanding how metabolites function as signaling molecules and modulate transcription. These metabolites or allosteric effector molecules bind to the repressor and alter the conformational equilibrium between the induced and the repressed st...

One Shift, Two Groups: When Fronting Alone Is Not Enough

When One Pipeline Is Not Enough

Pipelines that operate on buffers often work well to mitigate the high latency inherent in interprocessor communication and in accessing data on disk. Running a single pipeline on each node works well when each pipeline stage consumes and produces data at the same rate. If a stage might consume data faster or slower than it produces data, a single pipeline becomes unwieldy. We describe how we h...

When One Interactive System is Not Enough

The Art Institute of Chicago's pioneering development of public computer programs jump started with two fortuitous events. In 1987 the museum was asked to join a consortium of museum education directors from seven art museums whose main goal was to research and experiment with educational computer technology. Soon afterwards, the Art Institute became one of sixteen American institutions selecte...

Vision models for image quality assessment: one is not enough

A number of image quality metrics are based on psychophysical models of the human visual system. We propose a new framework for image quality assessment, gathering three indexes describing the image quality in terms of visual performance, visual appearance, and visual attention. These indexes are built on three vision models grounded on psychophysical data: we use models from Mantiuk et al. (vi...