Curcumin Protects against Cadmium-Induced Vascular Dysfunction, Hypertension and Tissue Cadmium Accumulation in Mice
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منابع مشابه
Curcumin Protects against Cadmium-Induced Vascular Dysfunction, Hypertension and Tissue Cadmium Accumulation in Mice
Curcumin from turmeric is commonly used worldwide as a spice and has been demonstrated to possess various biological activities. This study investigated the protective effect of curcumin on a mouse model of cadmium (Cd)-induced hypertension, vascular dysfunction and oxidative stress. Male ICR mice were exposed to Cd (100 mg/L) in drinking water for eight weeks. Curcumin (50 or 100 mg/kg) was in...
متن کاملCorrection: Tetrahydrocurcumin Protects Against Cadmium-Induced Hypertension, Raised arterial Stiffness and Vascular Remodeling in Mice
There is an error in the legend for Figure 3 “Effect of THU on the relative wall thickness (A), circumferential extension ratio (B), Ep (C), and Einc (D) of mice thoracic aortas in all experimental groups”. The complete, correct Figure 3 legend is: Figure 3. Results are expressed as mean ± SEM., n = 6–8/group. In animals not treated with Cd, THU has no effect on aortic elasticity of normal cont...
متن کاملTetrahydrocurcumin Protects against Cadmium-Induced Hypertension, Raised Arterial Stiffness and Vascular Remodeling in Mice
BACKGROUND Cadmium (Cd) is a nonessential heavy metal, causing oxidative damage to various tissues and associated with hypertension. Tetrahydrocurcumin (THU), a major metabolite of curcumin, has been demonstrated to be an antioxidant, anti-diabetic, anti-hypertensive and anti-inflammatory agent. In this study, we investigated the protective effect of THU against Cd-induced hypertension, raised ...
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Cadmium (Cd) is an environmental and industrial cumulative pollutant that most affects many organs specially the liver. The protective effect of Spirulina, filamentous blue green algae, on Cd – induced oxidative stress and hepatotoxicity was evaluated in male rats. Oral administration of water extract of Spirulina for seven days followed by an acute toxic dose of Cd (3.5 mg kg b.wt. ), reduced ...
متن کاملCurcumin Protects Mice Testicular Tissue against the Adverse Effects of Sodium Arsenite: A Stereological Study
Background & Aims: Sodium arsenite, an environmental pollutant, produces free radicals with harmful effects on the reproductive system. The aim of this study was to investigate the effect of curcumin, as a strong antioxidant, on the testis tissue and spermatogenic cell population in mice treated with sodium arsenite. Methods: In this experimental study, A...
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ژورنال
عنوان ژورنال: Nutrients
سال: 2014
ISSN: 2072-6643
DOI: 10.3390/nu6031194