منابع مشابه
Molecular Chaperone Dysfunction in Neurodegenerative Diseases and Effects of Curcumin
The intra- and extracellular accumulation of misfolded and aggregated amyloid proteins is a common feature in several neurodegenerative diseases, which is thought to play a major role in disease severity and progression. The principal machineries maintaining proteostasis are the ubiquitin proteasomal and lysosomal autophagy systems, where heat shock proteins play a crucial role. Many protein ag...
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ژورنال
عنوان ژورنال: BioFactors
سال: 2013
ISSN: 0951-6433
DOI: 10.1002/biof.1063