CtsR Regulation in mcsAB -Deficient Gram-Positive Bacteria

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CtsR regulation in mcsAB-deficient Gram-positive bacteria.

CtsR is an important repressor that modulates the transcription of class III stress genes in Gram-positive bacteria. In Bacillus subtilis, a model Gram-positive organism, the DNA binding activity of CtsR is regulated by McsAB-mediated phosphorylation of the protein where phosphorylated CtsR is a substrate for degradation by the ClpCP complex. Surprisingly, the mcsAB genes are absent from many G...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2012

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.06746-11