CT Hounsfield Units of Brown Adipose Tissue Increase with Activation: Preclinical and Clinical Studies
نویسندگان
چکیده
منابع مشابه
The calibration of CT Hounsfield units for radiotherapy treatment planning.
Computer tomographic (CT) scans are used to correct for tissue inhomogeneities in radiotherapy treatment planning. In order to guarantee a precise treatment, it is important to obtain the relationship between CT Hounsfield units and electron densities (or proton stopping powers for proton radiotherapy), which is the basic input for radiotherapy planning systems which consider tissue heterogenei...
متن کاملNonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans.
BACKGROUND Capsinoids-nonpungent capsaicin analogs-are known to activate brown adipose tissue (BAT) thermogenesis and whole-body energy expenditure (EE) in small rodents. BAT activity can be assessed by [¹⁸F]fluorodeoxyglucose-positron emission tomography (FDG-PET) in humans. OBJECTIVES The aims of the current study were to examine the acute effects of capsinoid ingestion on EE and to analyze...
متن کاملBrown adipose tissue
Obesity is currently a global pandemic, and is associated with increased mortality and co-morbidities including many metabolic diseases. Obesity is characterized by an increase in adipose mass due to increased energy intake, decreased energy expenditure, or both. While white adipose tissue is specialized for energy storage, brown adipose tissue has a high concentration of mitochondria and uniqu...
متن کاملBrown adipose tissue and thermogenesis.
The growing understanding of adipose tissue as an important endocrine organ with multiple metabolic functions has directed the attention to the (patho)physiology of distinct fat depots. Brown adipose tissue (BAT), in contrast to bona fide white fat, can dissipate significant amounts of chemical energy through uncoupled respiration and heat production (thermogenesis). This process is mediated by...
متن کاملVisualization of Brown Adipose Tissue
1Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2Molecular Epidemiology, Graduate School of Medicine, Kobe University, Kobe, Japan; 3First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan; 4Biology Laboratory Research Center, Daiichi Radioisotope Laboratories, Limited, Chiba, Japan; and 5Department of Anatomy, Meiji Colleg...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2010
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.109.068775