Crystallization of actin in complex with actin-binding proteins.

Utilization of paramagnetic relaxation enhancements for structural analysis of actin-binding proteins in complex with actin

Actin cytoskeleton dynamics are controlled by various actin binding proteins (ABPs) that modulate the polymerization of the monomeric G-actin and the depolymerization of filamentous F-actin. Although revealing the structures of the actin/ABP complexes is crucial to understand how the ABPs regulate actin dynamics, the X-ray crystallography and cryoEM methods are inadequate to apply for the ABPs ...

Endothelial Actin-Binding Proteins and Actin

Actin-binding proteins.

Actin is an essential component of the cytoskeleton and plays a crucial role in eukaryotic cells. The actin cytoskeleton functions in the generation and maintenance of cell morphology and polarity, in endocytosis and intracellular trafficking, in contractility, motility and cell division. In cells, the assembly and disassembly of actin filaments, and also their organisation into functional high...

Regulation of actin dynamics by actin-binding proteins in pollen.

A dynamic network of polymers, the actin cytoskeleton, co-ordinates numerous fundamental cellular processes. In pollen tubes, organelle movements and cytoplasmic streaming, organization of the tip zone, vesicle trafficking, and tip growth have all been linked to actin-based function. Further, during the self-incompatibility response of Papaver rhoeas, destruction of the cytoskeleton is a primar...

2122 Actin and actin-binding proteins in proliferative vitreoretinopathy

TITLE: HUMAN FIBROBLASTS PRODUCE AN OPTIMAL PVR EXPERIMENTAL MODEL. AUTHORS: GRACIA-MARTIN M.C., LIBERT J. AFFILIATION: Senior research fellow, Or. Gracia-Martin M.C Prof and Head of Dep., Or. Libert J. Dep. Ophthalmology St. Pierre Hosp., Brussels ABSTRACT: Purpose. Complex tractional retinal detachments show a low percentage of succesful reattachment, due to the development of oroliferative v...