Crystal Structure of Human Maspin, a Serpin with Antitumor Properties
نویسندگان
چکیده
منابع مشابه
Maspin (SERPINB5) is an obligate intracellular serpin.
Maspin (SERPINB5) is a tumor suppressor lost in breast and prostate cancer whose molecular function is unknown. It is a non-inhibitory member of the clade B serpins suggested to play a role in a plethora of intracellular and extracellular settings, yet its normal cellular distribution has never been clarified. Here we investigate the distribution of maspin in non-transformed human epithelial ce...
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4 School of Biological Sciences, University of East Anglia, Norwich, Norfolk, NR4 7TJ, UK 5 Anglia Ruskin IT Research Institute (ARITI), Anglia Ruskin University, Cambridge, CB1 1PT, UK 6 Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK. Corresponding author: [email protected], telephone +44 (0)191 227489...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2004
ISSN: 0021-9258
DOI: 10.1074/jbc.m409957200