Cryptococcal meningitis as a complication of systemic lupus erythematosus treated with systemic corticosteroids

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Cryptococcal meningitis as a complication of systemic lupus erythematosus treated with systemic corticosteroids.

Cryptococcosis, a disease of world-wide distribution, is uncommon in the British Isles where it usually presents as meningitis affecting patients with malignant disease of the reticulo-endothelial system, diabetes mellitus or those receiving systemic treatment with corticosteroids. The clinical features and physical signs of the disease are often non-specific and resemble those of tuberculous m...

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Cryptococcal meningitis in steroid-treated systemic lupus erythematosus.

A case of cryptococcal meningitis complicating steroidtreated systemic lupus erythematosus (SLE) which was successfully treated with amphotericin B is described. Although apparently rare, this mycotic infection has been reported from six patients with SLE in the medical literature over the past 10 years. Four of the six had been treated with steroids for periods ranging from 10 weeks to 6 years...

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Cryptococcal meningitis complicating systemic lupus erythematosus : two patients treated with flucytosine and amphotericin

Two fatal cases of cryptococcal meningitis complicating adrenocorticosteroid-treated systemic lupus erythematosus are reported. In one patient who was treated with flucytosine alone, after an initial period of improvement cryptococci resistant to flucytosine were isolated, and subsequent amphotericin B treatment did not alter the progress of the disease. In the second patient, who received both...

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A Case of Systemic Lupus Erythematosus

SUMMARY During the course of systemic lupus erythematosus in a 10 year-old girl, a go it er develo ped. Subc linical I ly pothyrnic.Jism was found, in addition rising titer of ant imicrosomal antibody and overt hypothyroidism after 6-week cessation of thyroxin tablet lead to the diagnosis of Hashimoto's thyroiditis. Antibodies directed to the thyroid may result in an autoimmune thyroiditis in...

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Cryptococcal meningitis complicating systemic lupus erythematosus: two patients treated with flucytosine and amphotericin B.

Two fatal cases of cryptococcal meningitis complicating adrenocorticosteroid-treated systemic lupus erythermatosus are reported. In one patient who was treated with flucytosine alone, after an initial period of improvement cryptococci resistant to flucytosine were isolated, and subsequent amphotericine B treatment silated, and subsequent amphotericin B treatment did not alter the progress of th...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1972

ISSN: 0032-5473

DOI: 10.1136/pgmj.48.555.52