Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear

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Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear.

The sense of balance depends on the intricate architecture of the inner ear, which contains three semicircular canals used to detect motion of the head in space. Changes in the shape of even one canal cause drastic behavioral deficits, highlighting the need to understand the cellular and molecular events that ensure perfect formation of this precise structure. During development, the canals are...

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ژورنال

عنوان ژورنال: Development

سال: 2008

ISSN: 1477-9129,0950-1991

DOI: 10.1242/dev.029330