Cross-reactive Immunity among Different Serotypes of Virus Causing Haemorrhagic Fever with Renal Syndrome
نویسندگان
چکیده
منابع مشابه
Cross-reactive immunity among different serotypes of virus causing haemorrhagic fever with renal syndrome.
Spleen cells primed by Prospect Hill (PH) or Puumala (Pu) virus could cross-react with Hantaan virus (HV) 76-118 strain-infected target cells after in vitro stimulation with HV-infected cells, although anti-PH or anti-Pu immune serum showed no cross-reactive neutralizing (NT) activity to HV without complement. These results and our previous findings with cross-reactive cytotoxic T lymphocytes (...
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Haemorrhagic fever with renal syndrome is a syndrome seen in diseases of varying severity which occur from the Far East across to Western Europe. The most common diseases in the Far East are Korean haemorrhagic fever and epidemic haemorrhagic fever, which are characterised by fever, muscular pains, haemorrhagic manifestations, and proteinuria; the complications of shock and renal failure may le...
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Newborn (within 24 h after birth), 1-week-old and 6-week-old (adult) rats were inoculated with a Hantaan-related virus (B-1) and attempts were made to isolate the virus from various organs. Virus-specific antigens were detected in various organs of newborn rats. Moreover virus could be isolated from almost all their organs even 25 weeks after infection. In contrast, in rats infected at 6 weeks ...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1989
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-70-4-819