Critical Illness Neuromuscular Disease

Critical illness neuromuscular disease: clinical, electrophysiological, and prognostic aspects.

BACKGROUND Critical illness neuromuscular disease, which has been recognised as a distinct clinical entity in adults, remains poorly described in children. AIMS To assess retrospectively the clinical, electrophysiological, and prognostic features of the disease. METHODS Retrospective study in a children's university hospital. RESULTS Five critically ill patients presented with generalised...

Electrophysiology of neuromuscular disorders in critical illness.

INTRODUCTION Neuromuscular disorders, predominantly critical illness myopathy (CIM) and critical illness polyneuropathy (CIP) occur in approximately one-third of patients in intensive care units. The aim of this study was to review the important role of electrophysiology in this setting. RESULTS In CIM, sarcolemmal inexcitability causes low amplitude compound muscle action potentials (CMAPs) ...

Acquired Neuromuscular Weakness in Critical Illness

Neuromuscular Blocking Agents and Neuromuscular Dysfunction Acquired in Critical Illness: A Systematic Review and Meta-Analysis.

OBJECTIVE The relationship between neuromuscular blocking agents and neuromuscular dysfunction acquired in critical illness remains unclear. We examined the association between neuromuscular blocking agents and ICU-acquired weakness, critical illness polyneuropathy, and critical illness myopathy. DATA SOURCES PubMed, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials, Cumu...

Ebola virus disease and critical illness

As of 20 May 2016 there have been 28,646 cases and 11,323 deaths resulting from the West African Ebola virus disease (EVD) outbreak reported to the World Health Organization. There continue to be sporadic flare-ups of EVD cases in West Africa.EVD presentation is nonspecific and characterized initially by onset of fatigue, myalgias, arthralgias, headache, and fever; this is followed several days...