Critical Cerebral Perfusion Pressure at High Intracranial Pressure Measured by Induced Cerebrovascular and Intracranial Pressure Reactivity
نویسندگان
چکیده
منابع مشابه
Effect of cerebral perfusion pressure on cerebral cortical microvascular shunting at high intracranial pressure in rats.
BACKGROUND AND PURPOSE Recently, we showed that decreasing cerebral perfusion pressure (CPP) from 70 mm Hg to 50 mm Hg and 30 mm Hg by increasing intracranial pressure (ICP) with a fluid reservoir induces a transition from capillary (CAP) to microvascular shunt (MVS) flow in the uninjured rat brain. This transition was associated with tissue hypoxia, increased blood-brain barrier (BBB) permeabi...
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Ten patients with intracranial lesions, anaesthetized with thiopentone and nitrous oxide (70%) in oxygen (30%) received etomidate 0.2 mg kg-1 i.v. Ventilation was controlled in each patient. Intracranial pressure (i.c.p.) and mean arterial pressure (m.a.p.) were recorded. I.c.p. decreased significantly in all patients (0.01 greater than P greater than 0.001). Although PaCO2 decreased during the...
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OBJECTIVES To examine changes in cerebrovascular pressure transmission derived from arterial blood pressure (ABP) and intracranial pressure (ICP) recordings by autoregressive moving average modeling technique. METHODS Digitized ICP and ABP recordings were obtained from patients with brain injury. Two groups were defined: Group A with 4 patients who demonstrated plateau waves, and Group B with...
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The treatment of traumatic brain injury is based on the conceptual distinction between primary and secondary injury. Primary injury comprises the immediate effects of impact. Secondary injury is due to factors other than the direct impact and may begin almost immediately or some time later. The distinction is of course, not so sharp. It is increasingly clear that the impact initiates a series o...
متن کاملCerebral Hemodynamics through Intracranial Pressure
Traumatic Brain Injury (TBI) continues to be a major problem worldwide. Today, intensive care of patients with TBI is mainly focused on preventing and treating secondary brain injuries. High pressure inside the intracranial cavity has been found to be an important feature of disturbed cerebral dynamics and secondary injuries. Thus, invasive measurement of intracranial pressure (ICP) is today a ...
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ژورنال
عنوان ژورنال: Critical Care Medicine
سال: 2014
ISSN: 0090-3493
DOI: 10.1097/ccm.0000000000000655