CRISPR RNA–guided activation of endogenous human genes
نویسندگان
چکیده
منابع مشابه
TALE activation of endogenous genes in Chlamydomonas reinhardtii
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Citation: Müller-Esparza H and Randau L (2017) Commentary: Type I CRISPR-Cas targets endogenous genes and regulates virulence to evade mammalian host immunity. Type-I CRISPR-Cas systems are abundant antiviral defense systems of bacteria and archaea. The hallmark sequences of these systems are short CRISPR RNAs (crRNAs) that contain spacer sequences which guide an interference complex termed Cas...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2013
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.2598