Cranial and trunk neural crest cells use different mechanisms for attachment to extracellular matrices

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Cranial and trunk neural crest cells use different mechanisms for attachment to extracellular matrices.

We have used a quantitative cell attachment assay to compare the interactions of cranial and trunk neural crest cells with the extracellular matrix (ECM) molecules fibronectin, laminin and collagen types I and IV. Antibodies to the beta 1 subunit of integrin inhibited attachment under all conditions tested, suggesting that integrins mediate neural crest cell interactions with these ECM molecule...

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ژورنال

عنوان ژورنال: Development

سال: 1992

ISSN: 1477-9129,0950-1991

DOI: 10.1242/dev.116.3.531