Cox4i2 Triggers an Increase in Reactive Oxygen Species, Leading to Ferroptosis and Apoptosis in HHV7 Infected Schwann Cells
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چکیده
منابع مشابه
Cuscuta campestris induces apoptosis by increasing reactive oxygen species generation in human leukemic cells
Objective: Cuscuta campestris or common dodder is a holoparasitic plant that has been valorized for treatment of liver injury and cancer prevention in traditional medicine. Recently, extract of C. campestris had shown moderate antimicrobial properties and cytotoxic effects. In this study, we examined the level of cellular oxidants, cytotoxicity, apoptosis and differentiation induced by hydr...
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Sulforaphane, an isothiocyanate found in cruciferous vegetables, has been shown to possess growth-inhibiting and apoptosis-inducing activities in cancer cell lines in vitro. In order to further explore the critical events leading to apoptosis in sulforaphane-treated U937 human leukemia cells, the following effects of sulforaphane on components of the mitochondrial apoptotic pathway were examine...
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Generation of reactive oxygen species (ROS) by diverse anti-cancer drugs or phytochemicals has been closely related with the induction of apoptosis in cancers. Also, the downregulation of ROS by these chemicals has been found to block initiation of carcinogenesis. Therefore, modulation of ROS by phytochemicals emerges as a crucial mechanism to regulate apoptosis in cancer prevention or therapy....
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ژورنال
عنوان ژورنال: Frontiers in Molecular Biosciences
سال: 2021
ISSN: 2296-889X
DOI: 10.3389/fmolb.2021.660072