Covid19 Drug Efficacy Statistical Analysis

Experimental design and statistical analysis for three-drug combination studies.

Drug combination is a critically important therapeutic approach for complex diseases such as cancer and HIV due to its potential for efficacy at lower, less toxic doses and the need to move new therapies rapidly into clinical trials. One of the key issues is to identify which combinations are additive, synergistic, or antagonistic. While the value of multidrug combinations has been well recogni...

Statistical Analysis Methods for the fMRI Data

Functional magnetic resonance imaging (fMRI) is a safe and non-invasive way to assess brain functions by using signal changes associated with brain activity. The technique has become a ubiquitous tool in basic, clinical and cognitive neuroscience. This method can measure little metabolism changes that occur in active part of the brain. We process the fMRI data to be able to find the parts of br...

Statistical analysis of immigrants to Abyssinia

immigration to Abyssinia, which took place at the beginning of the official invitation of the Prophet (PBUH) in the fifth year of the Besat, is of the most important events in the history of Islam. There are few historical documents of this immigration. Lack of information has prevented proper historical research about this immigration. Hence, the causes, manner and consequences of immigrating ...

CYP2C8 and antimalaria drug efficacy.

Malaria is a major infectious disease. In the last 10 years it has killed more than 20 million people, mainly small children in Africa. The highly efficacious artemisinine combination therapy is being launched globally, constituting the main hope for fighting the disease. Amodiaquine is a main partner in these combinations. Amodiaquine is almost entirely metabolized by the polymorphic cytochrom...

dismissing appropriate statistical analysis