COVID-19: Underlying Adipokine Storm and Angiotensin 1-7 Umbrella

COVID-19 and nail (7)

Although skin manifestations of COVID-19 were reported later than major organs affected, but it seems that they have gained relatively defined and definite described patterns. Regardless of strength and quantity of published papers and reports of rare cases, generally reported cutaneous manifestations are similar. However affection of vairous nail lesions have been mentioned recently. Even thou...

Angiotensin-(1-7).

Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog.

The in vivo efficacy of many therapeutic peptides is hampered by their rapid proteolytic degradation. Cyclization of these therapeutic peptides is an excellent way to render them more resistant against breakdown. Here, we describe the enzymatic introduction of a thioether ring in angiotensin [Ang-(1-7)], a heptapeptide that plays a pivotal role in the renin-angiotensin system and possesses impo...

The evaluation of clinical symptoms and underlying factors in infected patients with Covid-19

Background: The pandemic of Covid-19 is spreading around the world. Extensive research is needed to focus on identifying the underlying causes of the disease. This study aimed to investigate the clinical and etiological symptoms of the Covid-19. Methods: This descriptive-analytical study, conducted on 510 infected patients in the infectious disease clinic of Imam Khomeini Hospital in Tehran fr...

Cerebral Venous Thrombosis (CVT) following COVID-19 vaccination: an umbrella review of systematic reviews

Background and Objective: This umbrella review presents comprehensive data on the evidence of the association between cerebral venous thrombosis (CVT) and COVID-19 vaccinations. Methods: We searched related databases to access issue-related systematic reviews both with meta‐analyses or without it that studied the connotation between COVID 19 vaccination and CVT in any languages from initiatio...