Cover Picture: Electrochemical Detection of Tryptophan Metabolites via Kynurenine Pathway by Using Nanocarbon Films (Electroanalysis 4/2022)
نویسندگان
چکیده
The cover image is based on the Research Article Electrochemical Detection of Tryptophan Metabolites via Kynurenine Pathway by Using Nanocarbon Films Dai Kato et al., DOI: 10.1002/elan.202100241, which part Special Collection Electroanalysis Based Carbon Nanomaterials.
منابع مشابه
Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia.
OBJECTIVE To estimate the association of maternal plasma concentrations of tryptophan and six kynurenine pathway metabolites with the risk of preeclampsia. METHODS The study was based on a subsample of 2,936 pregnant women who delivered singleton neonates in the Norwegian Mother and Child Cohort Study in 2002-2003. Maternal blood plasma was obtained at approximately gestational week 18 and wa...
متن کاملQuantitative determination of tryptophan metabolites (via kynurenine) in biologic fluids.
HE POSSIBILITY OF 1)ETERMINING QUANTITATIVF LY some products of tryptophan metabolism (1) has been examined previously by one of the authors. Paper chromatography was used as a tool for the separation of kynurenine, 3-hydroxykynurenine, anthranilic, 3-hydroxyanthranilic, kynurenic, and xanthurenic acids. The purpose of this paper is to report on the quantitative determination of these products ...
متن کاملTryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites.
Metabolites of the kynurenine pathway (KP) of tryptophan (TRP) degradation have been closely linked to the pathogenesis of several neurodegenerative disorders. Recent work has highlighted the therapeutic potential of inhibiting two critical regulatory enzymes in this pathway-kynurenine-3-monooxygenase (KMO) and tryptophan-2,3-dioxygenase (TDO). Much evidence indicates that the efficacy of KMO i...
متن کاملKynurenine pathway metabolites and suicidality
Suicide is a major global problem, claiming more than 800,000 lives annually. The neurobiological changes that underlie suicidal ideation and behavior are not fully understood. Suicidal patients have been shown to display elevated levels of inflammation both in the central nervous system and the peripheral blood. A growing body of evidence suggests that inflammation is associated with a dysregu...
متن کاملL-tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice.
The activity of IDO that catalyzes the degradation of tryptophan (Trp) into kynurenine (Kyn) increases after diseases caused by different infectious agents. Previously, we demonstrated that IDO has an important immunomodulatory function in immune-related diseases. However, the pathophysiological role of IDO following acute viral infection is not fully understood. To investigate the role of IDO ...
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ژورنال
عنوان ژورنال: Electroanalysis
سال: 2022
ISSN: ['1040-0397', '1521-4109']
DOI: https://doi.org/10.1002/elan.202280401