Covalent and Non-Covalent Associations Mediate MED28 Homo- Oligomerization
نویسندگان
چکیده
منابع مشابه
Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization.
Some, perhaps all, G protein-coupled receptors form homo- or heterodimers. We have shown that metabotropic glutamate receptors are covalent dimers, held together by one or more disulfide bonds near the N terminus. Here we report how mutating cysteines in this region affect dimerization and function. Covalent dimerization is preserved when cysteines 57, 93, or 99 are mutated but lost with replac...
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ژورنال
عنوان ژورنال: Journal of Plant Biochemistry & Physiology
سال: 2017
ISSN: 2329-9029
DOI: 10.4172/2329-9029.1000189